![]() Low- Carb Diets & Coronary Blood Flow. Below is an approximation of this video’s audio content. To see any graphs, charts, graphics, images, and quotes to which Dr. Smart for Life is a popular cookie diet. While it's monitored by doctors, it also uses a controversial practice, hCG injections to jump-start weight loss. Free CSS.com. Free CSS has 2567 free website templates coded using HTML & CSS in its gallery. The HTML website templates that are showcased on Free CSS.com are the. Greger may be referring, watch the above video. People going on low- carb diets may not see a rise in their cholesterol levels. How is that possible? ![]() ![]() Because weight loss by any means can drop our cholesterol. We could go on an all- Twinkie diet and lower our cholesterol if we were unable to eat the dozen daily Twinkies necessary to maintain our weight. That’s why a good cocaine habit can lower cholesterol. Chemotherapy can drop cholesterol like a rock. Tuberculosis can work wonders on one’s waistline.
![]() Anything that drops our weight can drop our cholesterol. But, the goal isn’t to fit into a skinnier casket. The reason we care about cardiovascular risk factors like cholesterol is because we care about cardiovascular risk—the health of our arteries. Well, now we have studies that have measured the impact of low- carb diets on arteries directly, and a review of all the best studies done to date found that low- carb diets impair arterial function, as evidenced by a decrease in flow- mediated dilation—meaning low- carb diets effectively cripple people’s arteries. And, since the meta- analysis was published, another study found the same thing. A dietary pattern characterized by high protein and fat, low carbohydrate, was “associated with poorer peripheral small artery function”—again measuring blood flow into people’s limbs. Peripheral circulation is great, but what about circulation in the coronary arteries that feed our heart? There’s only been one study ever done measuring actual blood flow to the heart muscles of people eating low- carb diets, and this is it. Richard Fleming, an accomplished nuclear cardiologist, enrolled 2. SPECT scans—enabling him to actually directly measure the blood flow within the coronary arteries. He then put them all on a healthy vegetarian diet, and a year later, the scans were repeated. By that time, however, ten of the patients had jumped ship onto the low- carb bandwagon. At first, I bet he was upset, but surely soon realized he had an unparalleled research opportunity dropped into his lap. Here, he had extensive imaging on ten people following a low- carb diet, and 1. What would their hearts look like at the end of the year? We can talk about risk factors all we want, but compared to the veg group, did the coronary heart disease of the patients following the Atkins- like diets improve, worsen, or stay the same? Those sticking to the vegetarian diet showed a reversal of their heart disease, as expected. Their partially clogged arteries literally got cleaned out. They had 2. 0% less atherosclerotic plaque in their arteries at the end of the year than at the beginning. What happened to those who abandoned the treatment diet, and switched over to the low- carb diet? Their condition significantly worsened. Thanks to the kind generosity of Dr. Fleming, we can actually see the changes in blood flow for ourselves. Here are some representative heart scans. The yellow, and particularly red, represent blood flow through the coronary arteries to the heart muscle. This patient went on a plant- based diet, and their coronary arteries opened right up, increasing blood flow. This person, however, started out with good flow, but after a year on a low- carb diet, significantly clogged down their arterial blood flow. This is the best science to date demonstrating the threat of low- carb diets, not just measuring risk factors, but actual blood flow in people’s hearts on different diets. Of course, the reason we care about cardiac blood flow is we don’t want to die. And, a meta- analysis was recently published that finally went ahead and measured the ultimate endpoint, death, and “low- . Alzheimer's prevention: Diets, exercise and drug studies offer hope Ann Poehler’s strides quicken on the treadmill. Her feet pound. Her heart races from 1. A plastic tube jutting from the Prairie Village woman’s mouth feeds carbon dioxide levels to a computer here inside the University of Kansas Alzheimer’s Disease Center. The computer records every respiration while an exercise physiologist coaches her to push harder.“Can you hang in there like for 1. United States, just behind cancer. She watched Alzheimer’s rob her grandmother of her memory and life. Now her mother is in a memory care unit. Like millions of aging Americans, Poehler hopes to escape the cataclysm of the brain- wasting disease that now afflicts some 5. U. S., a number that only promises to grow as baby boomers age, if a cure or preventive is not found. A national study, published online Monday in the journal JAMA Internal Medicine, offered positive signs on what has long been a bleak landscape. It showed that the rate of dementia in people 6. The fact remains that one out of every three people over age 8. U. S. It’s in my family. So I would love for this study, or the studies that are going on right now, to affect my life. That would be the best.”Researchers at the KU Alzheimer’s Disease Center think so, too. Over the past five years, the center at 4. Shawnee Mission Parkway in Fairway has established itself as one of the top research centers in the nation dedicated to attacking Alzheimer’s disease. In 2. 01. 1, the National Institute on Aging, part of the National Institutes of Health, awarded the KU center $6 million over five years for research. Last month, the center won an additional $8. The National Institutes of Health has designated it one of 3. Alzheimer’s. Each center has its own Alzheimer’s research mission. At KU, the focus is on prevention — stalling or stopping the disease by looking precisely into how exercise, experimental medications and diet (including a low- carb Mediterranean diet heavy on fish, nuts and olive oil) may boost the body’s metabolism to combat or protect against the disease. No one has found a single cause or cure for Alzheimer’s. Only two classes of drugs even exist to stall some symptoms, with the most recent drug approved by the Food and Drug Administration 1. But strides are being made on every front. Research at KU has so expanded since 2. Alzheimer’s studies — that the center is now actively looking to enroll 7. Alzheimer’s, as well as those with some impairment) to be part of studies on exercise, diet and medication over the next three to five years. Fourteen studies are now underway, with more coming. In October, the Washington- based Global Alzheimer’s Platform Foundation — tasked with increasing the nation’s pool of study volunteers, thus hastening therapies to market — announced the formation of “K. C. Memory Strings Alliance” among local physicians’ groups, large area employers and others to help point volunteers toward studies. But it is a hopeful time,” said physician and researcher Jeffrey Burns, who co- directs the center and its studies with director, physician and researcher Russell Swerdlow. He coached basketball, too.“Jeff Burns was a student of mine,” Royer, 6. Alzheimer’s physician, whom Royer also coached as a player. Now it’s one of Burns’ studies putting Royer through his paces. Like Poehler, Royer is part of a study called APEX, Alzheimer’s Prevention Through Exercise. Also like Poehler, he is cognitively normal, with no memory problems or any other impairments. But his family has a history of Alzheimer’s.“I have my grandfather and my mother,” Royer said. His grandfather died of the disease in his 9. Royer’s mother, Jill Peck Royer, now 9. Royer first noticed it when he took his mother, a member of the Pi Beta Phi sorority at KU, to a university in Michigan for the celebration of a chapter she helped start there some 5. It was apparent she was slipping,” Royer said. She had a very impressive intellect, an incredible vocabulary.”Some six months ago, there were danger signs, Royer said, including the day she put a pot of water on the stove, forgot it was there and allowed it to boil dry. She now lives in a memory care unit in her hometown of Abilene, Kan. Although neither Royer nor Poehler is cognitively impaired, each received a free PET scan — positive emission tomography — to search for clues to Alzheimer’s as part of their initial work- up for the exercise study. In the past, Alzheimer’s could be diagnosed only at death through an autopsy. But within the last three years, PET brain scans have become available at major Alzheimer’s centers. The scans are extremely expensive, costing about $5,0. Neither Medicare nor insurance pays for them, although a national study, known as the i. DEAS study, was recently launched at centers including KU to assess whether Medicare should pick up the cost. For Royer and Poehler, the brain scans clearly showed low- level deposits of beta- amyloid protein plaques, one of the two main hallmarks of the disease. The condition is named for German psychiatrist Alois Alzheimer, who made his mark on history in 1. He also found tangles of what are now known as tau (rhymes with “now”) protein. Plaque deposits, which build up in the spaces between cells, and tangles, which clog the inside of cells, are thought to be the main culprits behind the brain cell death that leads to Alzheimer’s calamitous effects. A vital note, however, is that just because people have plaques and tangles doesn’t mean they absolutely will develop clinical Alzheimer’s. Right now, about one out of every three people over age 6. Higher levels put individuals at higher risk. But it is not at all clear if they will be hit by the disease’s memory loss or dementia. At KU, Burns pulled up several scans with glowing yellow areas that showed the brains to be swathed in the clogging protein. Yet the patients were cognitively normal. Why do some people with plaques and tangles get Alzheimer’s and others do not? It could have much to do with the amount or concentration of plaques and tangles, how much they expand, the rate at which they expand or the parts of the brain they affect. Researchers now think that for people who eventually develop Alzheimer’s, deposits of amyloid plaque may begin to build up as early as 1. The point of the APEX study is to assess whether regular and moderately intense aerobic exercise can slow the development of plaques and tangles and perhaps stall the disease. Four times each week, Royer drives to the YMCA in Olathe. He puts on a heart monitor and steps onto the treadmill. There, he exercises, as the study demands, for 3. He will do this for a year, raising the goal for his breathing and heart rate as he goes.“I don’t think I’m doing it for me,” Royer said after he ended his workout. Studies have shown that the more fit people are, the greater their aerobic capacity, the less brain shrinkage they have. APEX will chart the differences in the accumulation of brain amyloid in those who exercise regularly and those who do not.“We think exercise might actually modify the disease process,” Burns said. Knowing precisely how exercise affects a healthy brain will help determine ways to keep brains healthy. KU researchers will work with Alzheimer’s researchers at Northeastern University, the University of Pittsburgh and the University of Illinois to use brain images, plaque scans, blood work and a battery of physical and psychosocial tests to measure individuals in three groups: volunteers who exercise with moderate intensity for 1. Our advice we boil down to this,” Burns said. And we’re working hard to prove it.”Mediterranean diet That a healthy diet leads to a healthy heart is uncontested. Whether there is a precise type of diet that protects against Alzheimer’s dementia, however, is far less clear. Different studies offer differing evidence. Most studies, and most Alzheimer’s experts, agree that smoking is a risk factor for dementia. So is diabetes. A 2. American Journal of Psychiatry concluded that people with diabetes who have the kind of mild cognitive impairment seen in the early stages of Alzheimer’s tend to be more likely to progress to full Alzheimer’s dementia than those without diabetes. Monday’s study in JAMA Internal Medicine calculated that diabetes increased the risk of dementia, for which Alzheimer’s is the greatest cause, by 3. After that, data can be confusing. For example, a variety of studies holds that people with midlife obesity are at greater risk for dementia. Yet a recent analysis that was published in 2. The Lancet Diabetes & Endocrinology, looking at data on some 2 million people over two decades, found exactly the opposite: Overweight and perhaps even obese people at midlife were at lower risk of dementia. Those who were underweight were at greater risk. The study published Monday again backs this up, showing that being overweight or obese was tied to a 3. Some studies show that high blood pressure is a risk factor; others have found that later- life hypertension may protect against cognitive decline. Same with high cholesterol. Some studies show it’s bad, others not so much. But so far, what’s broadly called the Mediterranean diet stands out. The term describes a way of eating practiced by people in the countries surrounding the Mediterranean Sea — plenty of fish, olive oil, whole grains, lean protein and lots of fresh fruits, nuts, berries and vegetables. It limits sugars, refined carbohydrates and unhealthy fats, like from fried foods. Mediterranean people who eat that way tend to have lower rates of a number of diseases, including cancers, Parkinson’s and heart disease. In 2. 01. 3, a meta- analysis in the journal Epidemiology reviewed a dozen studies on the diet regarding dementia. It concluded that nine of 1. Alzheimer disease.” At the KU center, researchers recently finished a small, 2. The results, not yet in, will help determine whether KU will launch a larger study.
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